Short answer, yes.
Here's a link to one option, but there are more: http://neverwinterva...rsistent-worlds
Alot depends on how many servers you'll use. Some multicore computers with multiple game installations could support a Portal Module along with the two different playing modules. In some cases, launching multiple modules using NWNX2 will fail if all on the same server.
You could also not use a -Portal- module and simply add an option inside each module to access the other one.