One installation of NWN on a laptop with an Nvidia GeForce 860M worked fine under Win 8 and is now still working after transition to Win 10, only thing a bit quirky is getting it in focus and taking keyboard/mouse input after an alt-tab but one or a couple "Alt-F4" (then saying "No" when it prompts to exit) usually solve that. Resolution 1920*1080, fairly sure I had to edit the .ini for that but hey, needed to anyway to remove intro movies and make it play nice with windowed mode & so on.
The other installation on a desktop with a Radeon HD 7800 eventually worked fine under Win 7 Home Premium 64 bits (though IIRC I had to tweak it more than usual at first so it didn't crash on its face ALL. THE. TIME., it also really hated shiny water which made it stutter ridiculously for a game I ran first on something like a P450). It stopped working at some point before/during/after the transition to Win 10. But can't pinpoint why or when exactly since I just hadn't been using NWN on that machine for a while, and a full reinstallation + 1.69 critical rebuild got it back working. Resolution on that one is 1280*1024.
Both are in a directory OUT of program files or that couple other places later versions of Windows are a bit touchy about.
Version of the game is my old CDs from the french Deluxe Edition that included NWN + XP1 + XP2 but not the other couple premium modules I saw included in some later offers. So a bit younger than the original release but not by much.