You could remove the targeting glow from everything in the 2da - just to be uniform.
No, I'm not OCD. Really - hey is that picture hanging cockeyed again?
I actually did this for the last hak update on my own PW. At first, I considered undoing it, but have grown to actually like it. The only glitch, or rather mechanics issue, is that creatures no longer have the blinding auras, but their shields and weapons still glow red when hostile. It does make for a cleaner visual though when targeting IG.