Note - Although you can use the ini to set the affinity on a temp basis : you can however use Imagecfg.exe to set the affinity on the nwmain.exe executable permanently to be 1 core.
I use it because I found that the nwnplayer.ini setting wasnt working for me on Windows 7 64bit.
Note: If you have a server, you need to apply it to nwnserver.exe : otherwise it can suffer from rubber banding for the same reason that the game client would.
At least from experience I have had to -
( On a fresh server install - rubber banding, apply the image mask to 1 core affinity, and no rubber banding)
http://www2.robpol86...uides/ImageCFG/